Revealing the genomic differences between two subgroups in Lactobacillus gasseri

نویسندگان

  • Ipputa TADA
  • Yasuhiro TANIZAWA
  • Akihito ENDO
  • Masanori TOHNO
  • Masanori ARITA
چکیده

Being an autochthonous species in humans, Lactobacillus gasseri is widely used as a probiotic for fermented products. We thoroughly compared the gene contents of 75 L. gasseri genomes and identified two intraspecific groups by the average nucleotide identity (ANI) threshold of 94%. Group I, with 48 strains, possessed 53 group-specific genes including the gassericin T cluster (9 genes) and N-acyl homoserine lactone lactonase. Group II, with 27 strains, including the type strain ATCC 33323, possessed group-specific genes with plasmid- or phage-related annotations. The genomic differences provide evidences for demarcating a new probiotic group within L. gasseri.

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عنوان ژورنال:

دوره 36  شماره 

صفحات  -

تاریخ انتشار 2017